Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-50626
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues near the N terminal of human aryl-hydrocarbon receptor repressor
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2636079
Product Specific Information
The antibody detects endogenous levels of total AHRR protein.
Target Information
The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: AhR repressor; aryl hydrocarbon hydroxylase regulator; Aryl hydrocarbon receptor repressor; bHLHe77; Class E basic helix-loop-helix protein 77; dioxin receptor repressor
Gene Aliases: AHH; AHHR; AHRR; BHLHE77; KIAA1234; mKIAA1234
UniProt ID: (Human) A9YTQ3, (Mouse) Q3U1U7
Entrez Gene ID: (Human) 57491, (Mouse) 11624
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
response to xenobiotic stimulus
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
xenobiotic metabolic process
signal transduction
positive regulation of protein sumoylation
negative regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support