Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Proteintech
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Immunogen sequence: MAKWGEGDP RWIVEERADA TNVNNWHWTE RDASNWSTDK LKTLFLAVQV QNEEGKCEVT EVSKLDGEAS INNRKGKLIF FYEWSVKLNW TGTSKSGVQY KGHVEIPNLS DENSVDEVEI SVSLAKDEPD TNLVALMKEE GVKLLREAMG IYISTLKTEF TQGMILPTMN GESVDPVGQP ALKTEERKAK PAPSKTQARP VGVKIPTCKI TLKETFLTSP EELYRVFTTQ ELVQAFTHAP ATLEADRGGK FHMVDGNVSG EFTDLVPEKH IVMKWRFKSW PEGHFATITL TFIDKNGETE LCMEGRGIPA PEEERTRQGW QRYYFEGIKQ TFGYGARLF (1-338 aa encoded by BC000321 )
Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activator of 90 kDa heat shock protein ATPase homolog 1; Aha 1; AHA1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1; AHA1, activator of heat shock protein ATPase homolog 1; AHSA 1; p38; SHSA1
Gene Aliases: AHA1; AHSA1; BC023857; C14orf3; hAha1; HSPC322; p38
UniProt ID: (Human) O95433, (Mouse) Q8BK64
Entrez Gene ID: (Human) 10598, (Rat) 681996, (Mouse) 217737
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