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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • AID Antibodies

          Invitrogen

          AID Polyclonal Antibody

          1 Published Figure
          1 Reference
          View all (17) AID antibodies

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          Cite AID Polyclonal Antibody

          • Antibody Testing Data (3)
          • Published Figures (1)
          AID Antibody in Immunocytochemistry (ICC/IF)
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          AID Antibody in Immunocytochemistry (ICC/IF)
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          FIGURE: 1 / 4

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          AID Antibody (PA5-20012) in ICC/IF

          Immunocytochemistry of AID in Ramos cells with AID Polyclonal Antibody (Product # PA5-20012) at 10 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          AID Antibody in Immunocytochemistry (ICC/IF)
          AID Antibody in Immunocytochemistry (ICC/IF)
          AID Antibody in Western Blot (WB)
          AID Antibody in Immunocytochemistry (ICC/IF)

          Product Details

          PA5-20012

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          2 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          10 µg/mL
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A peptide corresponding to 14 amino acids near the carboxy terminus of human AID.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          0.02% sodium azide

          Storage conditions

          Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11154532

          Product Specific Information

          A suggested positive control is Ramos cell lysate.

          PA5-20012 can be used with blocking peptide PEP-0131.

          Target Information

          This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: activation induced deaminase; Activation-induced cytidine deaminase; AID; Cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; Single-stranded DNA cytosine deaminase

          View more View less

          Gene Aliases: AICDA; AID; ARP2; CDA2; HEL-S-284; HIGM2

          View more View less

          UniProt ID: (Human) Q9GZX7, (Mouse) Q9WVE0

          View more View less

          Entrez Gene ID: (Human) 57379, (Mouse) 11628

          View more View less

          Function(s)
          cytidine deaminase activity protein binding zinc ion binding ubiquitin protein ligase binding catalytic activity hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines metal ion binding
          Process(es)
          mRNA processing cytidine deamination somatic diversification of immunoglobulins somatic hypermutation of immunoglobulin genes B cell differentiation isotype switching cellular response to lipopolysaccharide DNA demethylation negative regulation of methylation-dependent chromatin silencing
          It has to be done as per old AB suggested Products section.
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