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Invitrogen
AID Monoclonal Antibody (1AID-2E11)
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FIGURE: 1 / 4
AID Antibody (MA3-081) in ICC/IF
Immunofluorescent analysis of AID (green) in NIH3T3 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.1% Triton X-100 in PBS for 15 minutes, and blocked with 3% BSA in PBS (Product # 37525) for 30 minutes at room temperature. Cells were stained with a AID mouse monoclonal antibody (Product # MA3-081) at a dilution of 1:100 in staining buffer for 1 hour at room temperature, and then incubated with a Goat anti-Mouse IgG Superclonal™ Secondary Antibody, Alexa Fluor 488 conjugate (Product # A28175) at a ... View More
Product Details
MA3-081
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1AID-2E11
Immunogen
Synthetic peptide coupled to Ovalbumin corresponding to aa 185 to 198 of mouse AID
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2633326
Product Specific Information
MA3-081 detects AID from human, and mouse samples.
MA3-081 has been successfully used in Western blot, immunofluorescence, flow cytometry, and ELISA applications.
The MA3-081 immunogen is the synthetic peptide coupled to ovalalbumin, aa 185 to 198. MA3-081 detects Isoform 1 (~24kDa) and Isoform 2 (~22kDa) in human samples.
Target Information
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: activation induced deaminase; Activation-induced cytidine deaminase; AID; Cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; Single-stranded DNA cytosine deaminase
Gene Aliases: AICDA; AID; ARP2; CDA2; HEL-S-284; HIGM2
UniProt ID: (Human) Q9GZX7, (Mouse) Q9WVE0
Entrez Gene ID: (Human) 57379, (Mouse) 11628
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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