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Invitrogen
AIP2 Polyclonal Antibody
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AIP2 Antibody (PA5-78355) in WB
AIP2 Polyclonal Antibody detects AIP2 protein by western blot analysis. Non-transfected (-) and AIP2 transfected (+) 293T whole cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with AIP2 Polyclonal Antibody (Product # PA5-78355) diluted at 1:500.
Product Details
PA5-78355
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human AIP2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735438
Product Specific Information
Positive Control: human WWP2-transfected 293T
Predicted Reactivity: Mouse (90%), Rat (90%), Dog (89%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (87%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AIP2; atrophin-1 interacting protein 2; Atrophin-1-interacting protein 2; HECT-type E3 ubiquitin transferase WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2; WW domain-containing protein 2
Gene Aliases: AIP2; WWP2; WWp2-like
UniProt ID: (Human) O00308
Entrez Gene ID: (Human) 11060
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cellular protein modification process
negative regulation of gene expression
protein ubiquitination
negative regulation of transporter activity
regulation of ion transmembrane transport
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
viral entry into host cell
negative regulation of protein transport
protein autoubiquitination
protein K63-linked ubiquitination
regulation of potassium ion transmembrane transporter activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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