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Product Details
PA5-78684
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the Intracellular domain of human AJAP1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.9 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735439
Product Specific Information
Positive Control: rat liver
Predicted Reactivity: Human (100%), Mouse (91%), Bovine (93%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
AJAP1, Adherens Junction Associated Protein 1, plays a key role in cell adhesion and cell migration. It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium. AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation. This facilitates the dissolution of adherens junctions with an increase in cell motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adherens junction associated protein 1; Adherens junction-associated protein 1; Membrane protein shrew-1; Neumo48; RP3426F10.1; transmembrane protein SHREW1
Gene Aliases: AJAP1; MOT8; Neumo48; SHREW-1; SHREW1
UniProt ID: (Human) Q9UKB5, (Rat) Q4W8E7
Entrez Gene ID: (Human) 55966, (Rat) 687031
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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