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Product Details
PA5-109373
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Ajuba (NP_1162651)
Conjugate
Form
Liquid
Concentration
0.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854784
Product Specific Information
Immunogen sequence: MERLGEKASR LLEKFGRRKG ESSRSGSDGT PGPGKGRLSG LGGPRKSGPR GATGGPGDEP LEPAREQGSL DAERNQRGSF EAPRYEGSFP AGPPPTRALP
Target Information
AJUBA (Ajuba LIM Protein) is a Protein Coding gene. Diseases associated with AJUBA include Wilson-Turner X-Linked Mental Retardation Syndrome and Syndromic X-Linked Intellectual Disability. Among its related pathways are Hippo signaling pathway and Adhesion. Gene Ontology (GO) annotations related to this gene include chromatin binding and actin filament binding. An important paralog of this gene is LIMD1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ajuba homolog; Ajuba protein; jub, ajuba homolog; LIM domain-containing protein ajuba; protein ajuba
Gene Aliases: AJUBA; JUB
UniProt ID: (Human) Q96IF1, (Mouse) Q91XC0, (Rat) Q5U2Z2
Entrez Gene ID: (Human) 84962, (Mouse) 16475, (Rat) 85265
negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
transcription, DNA-templated
regulation of transcription, DNA-templated
cell cycle
cell adhesion
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
lamellipodium assembly
regulation of cell migration
gene silencing by RNA
positive regulation of cellular biosynthetic process
positive regulation of protein complex assembly
negative regulation of kinase activity
positive regulation of kinase activity
cellular protein localization
gene silencing by miRNA
wound healing, spreading of epidermal cells
negative regulation of hippo signaling
regulation of GTPase activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAP kinase activity
glycerophospholipid biosynthetic process
focal adhesion assembly
regulation of cellular response to hypoxia
negative regulation of nucleic acid-templated transcription
positive regulation of gene silencing by miRNA
G2/M transition of mitotic cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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