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Proteintech
AK3 Polyclonal Antibody
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Product Details
12562-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AK3 Fusion Protein Ag3146 (1-227 aa encoded by BC013771)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGASARLLR AVIMGAPGSG KGTVSSRITT HFELKHLSSG DLLRDNMLRG TEIGVLAKAF IDQGKLIPDD VMTRLALHEL KNLTQYSWLL DGFPRTLPQA EALDRAYQID TVINLNVPFE VIKQRLTARW IHPASGRVYN IEFNPPKTVG IDDLTGEPLI QREDDKPETV IKRLKAYEDQ TKPVLEYYQK KGVLETFSGT ETNKIWPYVY AFLQTKVPQR SQKASVTP (1-227 aa encoded by BC013771)
Target Information
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adenylate kinase 3; Adenylate kinase 3 alpha-like 1; adenylate kinase 3 alpha-like 1 {ECO:0000255|HAMAP-Rule:MF_03169}; adenylate kinase 3 {ECO:0000255|HAMAP-Rule:MF_03169}; adenylate kinase 6, adenylate kinase 3 like 1; Adenylate kinase isozyme 3; AK 3; AK 3 {ECO:0000255|HAMAP-Rule:MF_03169}; AK3; AK4; GTP:AMP phosphotransferase AK3, mitochondrial; GTP:AMP phosphotransferase AK3, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03169}; GTP:AMP phosphotransferase mitochondrial; GTP:AMP phosphotransferase, mitochondrial
Gene Aliases: AA407498; AI506714; AK-3; AK3; Ak3l; AK3L1; AK6; AKL3L; AKL3L1; FIX
UniProt ID: (Human) Q9UIJ7, (Rat) P29411, (Mouse) Q9WTP7
Entrez Gene ID: (Human) 50808, (Rat) 26956, (Mouse) 56248
adenylate kinase activity
protein binding
ATP binding
GTP binding
nucleoside triphosphate adenylate kinase activity
identical protein binding
nucleotide binding
kinase activity
transferase activity
phosphotransferase activity, phosphate group as acceptor
nucleobase-containing compound kinase activity
liver development
ADP biosynthetic process
AMP phosphorylation
muscle organ development
cerebellum development
olfactory bulb development
response to starvation
AMP metabolic process
ATP metabolic process
GTP metabolic process
ITP metabolic process
UTP metabolic process
dATP metabolic process
nucleotide phosphorylation
protein homooligomerization
nucleobase-containing compound metabolic process
phosphorylation
blood coagulation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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