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This antibody detects endogenous protein at a molecular weight of 74 kDa.
Purity is >95% by SDS-PAGE.
The A-kinase anchor proteins are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A kinase (PRKA) anchor protein 10; A kinase anchor protein 10; A-kinase anchor protein 10, mitochondrial; AKAP-10; D-AKAP-2; Dual specificity A kinase-anchoring protein 2; MGC9414; mitochondrial A kinase PPKA anchor protein 10; PRKA10; protein kinase A anchoring protein 10; Protein kinase A-anchoring protein 10
Gene Aliases: AKAP-10; AKAP10; D-AKAP-2; D-AKAP2; PRKA10
UniProt ID: (Human) O43572
Entrez Gene ID: (Human) 11216
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