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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • AKAP4 Antibodies

          Proteintech

          AKAP4 Polyclonal Antibody

          2 References
          View all (9) AKAP4 antibodies

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          Cite AKAP4 Polyclonal Antibody

          • Antibody Testing Data (3)
          AKAP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          AKAP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 3

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          AKAP4 Antibody (24986-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 24986-1-AP ( AKAP4 Antibody) at dilution of 1:50 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          AKAP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          AKAP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          AKAP4 Antibody in Western Blot (WB)

          Product Details

          24986-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          AKAP4 Fusion Protein Ag21762 (565-693 aa encoded by BC126252)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.31 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: TCEEDCPGS TMGYMAQSTQ YEKCGGGQSA KALSVKQLES HRAPGPSTCQ KENQHLDSQK MDMSNIVLML IQKLLNENPF KCEDPCEGEN KCSEPRASKA ASMSNRSDKA EEQCQEHQEL DCTSGMKQAN (565-693 aa encoded by BC126252)

          Target Information

          The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm. It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways. AKAP4 has also been postulated to be a potential biomarker for breast cancer.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: A kinase (PRKA) anchor protein 4; A-kinase anchor protein 4; A-kinase anchor protein 82 kDa; AKAP 82; AKAP-4; AKAP4; cancer/testis antigen 99; HI; Major sperm fibrous sheath protein; PRKA4; protein kinase A anchoring protein 4; Protein kinase A-anchoring protein 4; testis-specific gene HI

          View more View less

          Gene Aliases: AKAP 82; AKAP-4; AKAP4; AKAP82; CT99; FSC1; hAKAP82; HI; p82; PRKA4

          View more View less

          UniProt ID: (Human) Q5JQC9

          View more View less

          Entrez Gene ID: (Human) 8852

          View more View less

          Function(s)
          protein kinase A binding
          Process(es)
          movement of cell or subcellular component signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway single fertilization regulation of protein kinase A signaling sperm motility motile cilium assembly establishment of protein localization
          It has to be done as per old AB suggested Products section.
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