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Invitrogen
AKR1B1 Polyclonal Antibody
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AKR1B1 Antibody (PA5-118399) in IHC (P)
Immunohistochemistry (Paraffin) analysis of AKR1B1 in paraffin-embedded human seminal vesicle tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with AKR1B1 polyclonal Antibody (Product # PA5-118399) at a dilution of 1:40... View More
Product Details
PA5-118399
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within human AKR1B1 aa 1-50
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 0.2% BSA, 50% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2902989
Target Information
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aldehyde reductase; aldehyde reductase 1; Aldehyde reductase 1 (low Km aldose reductase) (5.8 kb PstI fragment, probably the functional gene); aldo-keto reductase family 1; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1 (aldose reductase); aldo-keto reductase family 1, member B4 (aldose reductase); Aldose reductase; AR; Lii5-2 CTCL tumor antigen; low Km aldose reductase; member B1 (aldose reductase)
Gene Aliases: ADR; AKR1B1; Akr1b3; Akr1b4; ALDR1; ALDRED; Alr; ALR-P-I; ALR2; AR; RATALDRED
UniProt ID: (Human) P15121, (Rat) P07943
Entrez Gene ID: (Human) 231, (Rat) 24192
tissue homeostasis
carbohydrate metabolic process
sorbitol biosynthetic process
C21-steroid hormone biosynthetic process
response to stress
response to water deprivation
naphthalene metabolic process
stress-activated protein kinase signaling cascade
norepinephrine metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
fructose biosynthetic process
positive regulation of JAK-STAT cascade
positive regulation of smooth muscle cell proliferation
oxidation-reduction process
maternal process involved in female pregnancy
cellular response to hydrogen peroxide
inner medullary collecting duct development
response to thyroid hormone
cellular response to methylglyoxal
cellular response to peptide
monosaccharide metabolic process
response to organic substance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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