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This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish. The protein encoded by this gene interacts with maspardin, a protein that when truncated is responsible for Mast syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: aldehyde dehydrogenase 16 family, member A1; aldehyde dehydrogenase 16A1; Aldehyde dehydrogenase family 16 member A1
Gene Aliases: 2410004H02Rik; AI452234; ALDH16A1; mFLJ00209
UniProt ID: (Human) Q8IZ83, (Rat) Q3T1L0, (Mouse) Q571I9
Entrez Gene ID: (Human) 126133, (Rat) 361571, (Mouse) 69748
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