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Invitrogen
ALDH1A2 Polyclonal Antibody
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Product Details
PA5-144599
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
The immunogen used to generate this antibody corresponds to zebrafish Aldh1a2.
Conjugate
Form
Liquid
Concentration
1.02 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3090428
Target Information
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AL1A2; Aldh1a2; neckless; nls; no-fin; nof; RALDH2; retinaldehyde dehydrogenase 2
Gene Aliases: fb50h01; raldh2
Entrez Gene ID: (Zebrafish) 116713
somitogenesis
liver development
determination of left/right symmetry
anterior/posterior pattern specification
hindbrain morphogenesis
central nervous system myelination
myelination in peripheral nervous system
pancreas development
fin regeneration
pectoral fin development
pronephric duct morphogenesis
retinol metabolic process
retinoic acid metabolic process
axial mesoderm development
paraxial mesoderm development
retinoic acid receptor signaling pathway
regulation of retinoic acid receptor signaling pathway
digestive tract morphogenesis
camera-type eye morphogenesis
embryonic viscerocranium morphogenesis
pronephros development
oxidation-reduction process
face morphogenesis
pancreas field specification
glomerular visceral epithelial cell development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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