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ALDH1L2 Antibody (PA5-120273) in WB
Western blot analysis of ALDH1L2 in extracts of various cell lines. Samples were incubated with ALDH1L2 Polyclonal antibody (Product # PA5-120273) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-120273
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human ALDH1L2 (NP_001029345.2).
Conjugate
Form
Liquid
Concentration
2.25 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913845
Product Specific Information
Positive test controls include: Mouse pancreas, Rat pancreas, Rat liver. The target is usually found in the following locations: Mitochondrion.
Immunogen sequence: EPLEIKGAKK PGLVTKNGLV LFGNDGKALT VRNLQFEDGK MIPASQYFST GETSVVELTA EEVKVAETIK VIWAGILSNV PIIEDSTDFF KSGASSMDVA RLVEEIRQKC GGLQLQNEDV YMATKFEGFI QKVVRKLRGE DQEVELVVDY ISKEVNEIMV KMPYQCFING QFTDADDGKT YDTINPTDGS TICKVSYASL A
Target Information
This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 10-formyltetrahydrofolate dehydrogenase ALDH1L2; aldehyde dehydrogenase 1 family, member L2; aldehyde dehydrogenase 1L2; Aldehyde dehydrogenase family 1 member L2; aldehyde dehydrogenase family 1 member L2, mitochondrial; Mitochondrial 10-formyltetrahydrofolate dehydrogenase; Mitochondrial 10-FTHFDH; probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2
Gene Aliases: ALDH1L2; D330038I09Rik; mtFDH; RGD1309458
UniProt ID: (Human) Q3SY69, (Mouse) Q8K009
Entrez Gene ID: (Human) 160428, (Rat) 299699, (Mouse) 216188
aldehyde dehydrogenase (NAD) activity
formyltetrahydrofolate dehydrogenase activity
hydroxymethyl-, formyl- and related transferase activity
aminobutyraldehyde dehydrogenase activity
4-trimethylammoniobutyraldehyde dehydrogenase activity
methyltransferase activity
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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