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Product Details
PA5-85334
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ALDH3A1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.61 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792476
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (82%), Rat (83%), Dog (91%), Bovine (89%).
Positive Control: mouse eye, Whole Cornea.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorption of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alcohol dehydrogenase family 3, subfamily A1; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family, member A1; aldehyde dehydrogenase 3 family, memberA1; aldehyde dehydrogenase 3, stomach cytosolic (class 3); Aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A1; aldehyde dehydrogenase isozyme 3; aldehyde dehydrogenase type III; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHIII; BCP54; corneal 15.8 kDa protein; corneal protein 54, transparentin; dehydrogenase 3, dimeric NAPD-prefering; Dioxin-inducible aldehyde dehydrogenase 3; MGC10406; stomach aldehyde dehydrogenase; transparentin
Gene Aliases: Ahd-4; Ahd4; Aldh; ALDH3; ALDH3A1; Aldh4; ALDHIII; BOS_18909
UniProt ID: (Human) P30838, (Mouse) P47739
Entrez Gene ID: (Human) 218, (Bovine) 281617, (Mouse) 11670
3-chloroallyl aldehyde dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
aldehyde dehydrogenase [NAD(P)+] activity
protein binding
alcohol dehydrogenase (NADP+) activity
benzaldehyde dehydrogenase (NAD+) activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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