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Proteintech
ALDH6A1 Polyclonal Antibody
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Product Details
20452-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ALDH6A1 Fusion Protein Ag13879 (194-535 aa encoded by BC004909)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: WMFPMAMVC GNTFLMKPSE RVPGATMLLA KLLQDSGAPD GTLNIIHGQH EAVNFICDHP DIKAISFVGS NKAGEYIFER GSRHGKRVQA NMGAKNHGVV MPDANKENTL NQLVGAAFGA AGQRCMALST AVLVGEAKKW LPELVEHAKN LRVNAGDQPG ADLGPLITPQ AKERVCNLID SGTKEGASIL LDGRKIKVKG YENGNFVGPT IISNVKPNMT CYKEEIFGPV LVVLETETLD EAIQIVNNNP YGNGTAIFTT NGATARKYAH LVDVGQVGVN VPIPVPLPMF SFTGSRSSFR GDTNFYGKQG IQFYTQLKTI TSQWKEEDAT LSSPAVVMPT MGR (194-535 aa encoded by BC004909)
Target Information
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: aldehyde dehydrogenase 6 family, member A1; Aldehyde dehydrogenase family 6 member A1; aldehyde dehydrogenase family 6, subfamily A1; malonate-semialdehyde dehydrogenase; Malonate-semialdehyde dehydrogenase [acylating]; methylmalonate semialdehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial; MGC40271; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; MMSDH; testicular tissue protein Li 122
Gene Aliases: 1110038I05Rik; AI314632; ALDH6A1; MMSADHA; MMSDH
UniProt ID: (Human) Q02252, (Rat) Q02253, (Mouse) Q9EQ20
Entrez Gene ID: (Human) 4329, (Rat) 81708, (Mouse) 104776
fatty-acyl-CoA binding
aldehyde dehydrogenase (NAD) activity
methylmalonate-semialdehyde dehydrogenase (acylating) activity
thiolester hydrolase activity
malonate-semialdehyde dehydrogenase (acetylating) activity
poly(A) RNA binding
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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