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Invitrogen
ALOX12B Polyclonal Antibody
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ALOX12B Antibody (PA5-23608) in IHC (P)
Immunohistochemistry analysis of ALOX12B in formalin fixed and paraffin embedded human tonsil tissue. Samples were incubated with ALOX12B polyclonal antibody (Product # PA5-23608) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-23608
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 622-652 amino acids from the C-terminal region of human ALOX12B
Conjugate
Form
Liquid
Concentration
1.7 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2541108
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 12R-lipoxygenase; 12R-LOX; Arachidonate 12-lipoxygenase, 12R-type; Epidermis-type lipoxygenase 12
Gene Aliases: 12R-LOX; ALOX12B; ARCI2
UniProt ID: (Human) O75342
Entrez Gene ID: (Human) 242
protein lipidation
sphingolipid metabolic process
positive regulation of gene expression
arachidonic acid metabolic process
lipoxygenase pathway
positive regulation of MAPK cascade
linoleic acid metabolic process
ceramide biosynthetic process
hepoxilin biosynthetic process
oxidation-reduction process
establishment of skin barrier
positive regulation of mucus secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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