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Invitrogen
ALOX15 Monoclonal Antibody (OTI7H6)
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Product Details
MA5-25891
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI7H6
Immunogen
Full length human recombinant protein of ALOX15 produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2722849
Target Information
ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. The protein also acts on C-12 of arachidonate as well as on linoleic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 12-LOX; 12/15-lipoxygenase; 12/15-LO; 12/15-LOX; 15-lipooxygenase-1; 15-LOX; 15-LOX2; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase; Polyunsaturated fatty acid lipoxygenase ALOX15
Gene Aliases: 12-LO; 12-LOX; 12/15-LO; 15-LOX; 15-LOX-1; 15LOX-1; Alox12; Alox12l; ALOX15; L-12LO; LOG15
UniProt ID: (Human) P16050, (Mouse) P39654, (Rat) Q02759
Entrez Gene ID: (Human) 246, (Mouse) 11687, (Rat) 81639
arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
hepoxilin-epoxide hydrolase activity
arachidonate 15-lipoxygenase activity
hepoxilin A3 synthase activity
eoxin A4 synthase activity
lipid binding
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
dioxygenase activity
potassium channel inhibitor activity
ossification
negative regulation of adaptive immune response
phosphatidylethanolamine biosynthetic process
leukotriene metabolic process
inflammatory response
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
bone mineralization
positive regulation of actin filament polymerization
positive regulation of heterotypic cell-cell adhesion
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
apoptotic cell clearance
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process
lipid metabolic process
fatty acid metabolic process
positive regulation of cell proliferation
fatty acid oxidation
positive regulation of cell growth
regulation of membrane potential
negative regulation of apoptotic process
negative regulation of cell volume
icosanoid biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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