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          • Primary Antibodies ›
          • ALOX15B Antibodies

          Invitrogen

          ALOX15B Polyclonal Antibody

          View all (9) ALOX15B antibodies

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          Cite ALOX15B Polyclonal Antibody

          • Antibody Testing Data (2)
          ALOX15B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          ALOX15B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 2

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          ALOX15B Antibody (PA5-112355) in IHC (P)

          Immunocytochemical analysis of paraffin-embeded ALOX15B in human skin tissue using a ALOX15B Polyclonal antibody (Product # PA5-112355) at a dilution of 1:100. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ALOX15B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ALOX15B Antibody in Western Blot (WB)

          Product Details

          PA5-112355

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human Arachidonate 15-lipoxygenase B protein (1-200AA)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.89 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2867091

          Target Information

          ALOX15B encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 15-lipoxygenase 2; 15-LOX-2; 15-LOX-B; 15S-lipoxygenase; arachidonate 15-lipoxygenase 2; Arachidonate 15-lipoxygenase B; Arachidonate 15-lipoxygenase type II; arachidonate 15-lipoxygenase, second type; arachidonate omega(6) lipoxygenase; Linoleate 13-lipoxygenase 15-LOb; Polyunsaturated fatty acid lipoxygenase ALOX15B

          View more View less

          Gene Aliases: 15-LOX-2; ALOX15B

          View more View less

          UniProt ID: (Human) O15296

          View more View less

          Entrez Gene ID: (Human) 247

          View more View less

          Function(s)
          iron ion binding calcium ion binding lipid binding linoleate 13S-lipoxygenase activity arachidonate 8(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity
          Process(es)
          lipid metabolic process apoptotic process negative regulation of cell proliferation positive regulation of macrophage derived foam cell differentiation arachidonic acid metabolic process lipoxygenase pathway negative regulation of cell migration prostate gland development regulation of epithelial cell differentiation positive regulation of peroxisome proliferator activated receptor signaling pathway linoleic acid metabolic process positive regulation of keratinocyte differentiation negative regulation of cell cycle negative regulation of growth hepoxilin biosynthetic process oxidation-reduction process positive regulation of chemokine secretion
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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