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Invitrogen
ALY Polyclonal Antibody
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FIGURE: 1 / 5
ALY Antibody (PA5-22314) in ICC/IF
Immunocytochemistry (Confocal immunofluorescence) of ALY in paraformaldehyde-fixed HeLa. Samples were incubated with ALY polyclonal antibody (Product # PA5-22314) using a dilution of 1:500 (green). Alpha-tubulin filaments were labeled with alpha Tubulin monoclonal antibody (Product # MA1-25054) (Red) at 1:2,000.
Product Details
PA5-22314
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ALY. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.63 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11151976
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, Mouse brain.
Predicted reactivity: Mouse (96%), Rat (98%), Chicken (82%), Rhesus Monkey (98%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ally of AML-1 and LEF-1; Aly/REF export factor; bZIP enhancing factor; bZIP-enhancing factor BEF; REF1-I; RNA and export factor binding protein 1; RNA and export factor-binding protein 1; Tcra enhancer-binding factor interacting protein 1; THO complex 4; THO complex subunit 4; Tho4; Transcriptional coactivator Aly/REF
Gene Aliases: ALY; ALY/REF; ALYREF; BEF; REF; REF1; Refbp1; THOC4
UniProt ID: (Human) Q86V81, (Mouse) O08583
Entrez Gene ID: (Human) 10189, (Mouse) 21681
mRNA processing
transport
RNA splicing
mRNA transport
regulation of DNA recombination
mRNA splicing, via spliceosome
osteoblast differentiation
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA export from nucleus
mRNA 3'-end processing
replication fork processing
positive regulation of DNA-templated transcription, elongation
viral mRNA export from host cell nucleus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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