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Invitrogen
ALY Polyclonal Antibody
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Product Details
PA5-96489
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human THOC4/THOC4/ALYREF (NP_0057733)
Conjugate
Form
Liquid
Concentration
1.48 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808291
Product Specific Information
Positive Samples: HeLa, A-549, B cells, SKOV3, HL-60, Mouse testis, Mouse spleen, Mouse thymus, Rat brain; Cellular Location: Cytoplasm, Nucleus, Nucleus speckle
Immunogen sequence: MPDSAPAMAD KMDMSLDDII KLNRSQRGGR GGGRGRGRAG SQGGRGGGAQ AAARVNRGGG PIRNRPAIAR GAAGGGGRNR PAPYSRPKQL PDKWQHDLFD
Target Information
The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ally of AML-1 and LEF-1; Aly/REF export factor; bZIP enhancing factor; bZIP-enhancing factor BEF; REF1-I; RNA and export factor binding protein 1; RNA and export factor-binding protein 1; Tcra enhancer-binding factor interacting protein 1; THO complex 4; THO complex subunit 4; Tho4; Transcriptional coactivator Aly/REF
Gene Aliases: ALY; ALY/REF; ALYREF; BEF; REF; REF1; Refbp1; THOC4
UniProt ID: (Human) Q86V81, (Mouse) O08583
Entrez Gene ID: (Human) 10189, (Rat) 690585, (Mouse) 21681
regulation of DNA recombination
osteoblast differentiation
mRNA export from nucleus
replication fork processing
positive regulation of DNA-templated transcription, elongation
viral mRNA export from host cell nucleus
mRNA processing
transport
RNA splicing
mRNA transport
mRNA splicing, via spliceosome
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA 3'-end processing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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