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Invitrogen
AMER2 Polyclonal Antibody
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Product Details
PA5-70111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the middle region of human AMER2 (aa 39-88)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691072
Product Specific Information
This target displays homology in the following species: Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 93%
Target Information
Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Amer2; APC membrane recruitment protein 2; family with sequence similarity 123, member A; Protein FAM123A
Gene Aliases: 2600011E07Rik; Amer2; Fam123a
UniProt ID: (Mouse) Q8CCJ4
Entrez Gene ID: (Mouse) 72125
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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