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Invitrogen
AMHR2 Polyclonal Antibody
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Product Details
PA5-47168
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Sf 21-derived recombinant rat MIS RII Pro19-Pro144
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607343
Product Specific Information
In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) TGF- beta RII, rhTGF-beta RIII, recombinant mouse (rm) TGF-beta RI, and rmTGF-beta RII is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMH type II receptor; Anti-Muellerian hormone type II receptor; Anti-Muellerian hormone type-2 receptor; anti-Mullerian hormone receptor type 11 SV1; anti-Mullerian hormone type 2 receptor; C14; MIS type II receptor; MISRII; MRII
Gene Aliases: Amhr2
UniProt ID: (Rat) Q62893
Entrez Gene ID: (Rat) 29530
protein phosphorylation
signal transduction
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
sex differentiation
signal transduction by protein phosphorylation
negative regulation of anti-Mullerian hormone signaling pathway
anti-Mullerian hormone signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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