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Invitrogen
AMHR2 Recombinant Rabbit Monoclonal Antibody (7R5V8)
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FIGURE: 1 / 1
AMHR2 Antibody (MA5-55385) in WB
Western Blot analysis of various lysates using AMHR2 Recombinant Monoclonal Antibody (Product # MA5-55385) at 1:2,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
MA5-55385
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7R5V8
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 18-144 of human AMHR2.
Conjugate
Form
Liquid
Concentration
0.84 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
RRID
AB_3667626
Product Specific Information
Immunogen Sequence: PPNRRTCVFF EAPGVRGSTK TLGELLDTGT ELPRAIRCLY SRCCFGIWNL TQDRAQVEMQ GCRDSDEPGC ESLHCDPSPR AHPSPGSTLF TCSCGTDFCN ANYSHLPPPG SPGTPGSQGP QAAPGES
Target Information
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMH type II receptor; Anti-Muellerian hormone type II receptor; Anti-Muellerian hormone type-2 receptor; anti-Mullerian hormone receptor type II; anti-Mullerian hormone receptor, type II; anti-Mullerian hormone type 2 receptor delta 2; anti-Mullerian hormone type 2 receptor delta 9/10; MIS type II receptor; MISRII; Muellerian inhibiting substance type II receptor; Mullerian inhibiting substance type II receptor
Gene Aliases: AMHR; AMHR2; Misiir; MISR2; MISRII; MRII
UniProt ID: (Human) Q16671, (Mouse) Q8K592
Entrez Gene ID: (Human) 269, (Mouse) 110542
receptor signaling protein serine/threonine kinase activity
receptor activity
transforming growth factor beta receptor activity, type II
protein binding
ATP binding
hormone binding
metal ion binding
anti-Mullerian hormone receptor activity
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
transforming growth factor beta-activated receptor activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein phosphorylation
signal transduction
transmembrane receptor protein serine/threonine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
sex differentiation
phosphorylation
negative regulation of anti-Mullerian hormone signaling pathway
anti-Mullerian hormone signaling pathway
Mullerian duct regression
male gonad development
female gonad development
signal transduction by protein phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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