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Invitrogen
AMPK alpha-1 Monoclonal Antibody (167CT22.1.6)
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Product Details
MA5-37483
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
167CT22.1.6
Immunogen
PRKAA1 recombinant protein
Conjugate
Form
Liquid
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897416
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; AAPK2; ACACA kinase; Acetyl-CoA carboxylase kinase; activated protein kinase; AMP -activate kinase alpha 1 subunit; AMP activated protein kinase; AMP-activated protein kinase, catalytic, alpha-1; AMPK alpha 1; AMPK subunit alpha-1; AMPK subunit pAMPK; AMPK-alpha-2 chain; AMPK2; HMGCR kinase; Hydroxymethylglutaryl-CoA reductase kinase; MGC33776; MGC57364; pAMPK; PRKAA; PRKAA2; protein kinase, AMP-activated, alpha 1 catalytic subunit; Tau-protein kinase PRKAA1
Gene Aliases: AMPK; AMPK1; AMPKa1; PRKAA1
UniProt ID: (Human) Q13131
Entrez Gene ID: (Human) 5562
chromatin binding
protein kinase activity
AMP-activated protein kinase activity
cAMP-dependent protein kinase activity
protein binding
ATP binding
protein C-terminus binding
kinase binding
histone serine kinase activity
metal ion binding
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
tau-protein kinase activity
[acetyl-CoA carboxylase] kinase activity
activation of MAPK activity
response to hypoxia
glucose metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
fatty acid biosynthetic process
cholesterol biosynthetic process
cell cycle arrest
signal transduction
positive regulation of cell proliferation
lipid biosynthetic process
response to UV
cold acclimation
response to gamma radiation
positive regulation of autophagy
positive regulation of gene expression
response to activity
Wnt signaling pathway
macroautophagy
fatty acid oxidation
response to caffeine
cellular response to nutrient levels
negative regulation of TOR signaling
regulation of peptidyl-serine phosphorylation
histone-serine phosphorylation
intracellular signal transduction
cellular response to glucose starvation
glucose homeostasis
regulation of circadian rhythm
negative regulation of apoptotic process
positive regulation of cholesterol biosynthetic process
positive regulation of glycolytic process
negative regulation of glucosylceramide biosynthetic process
rhythmic process
positive regulation of skeletal muscle tissue development
negative regulation of lipid catabolic process
protein heterooligomerization
fatty acid homeostasis
regulation of vesicle-mediated transport
cellular response to hydrogen peroxide
cellular response to ethanol
cellular response to prostaglandin E stimulus
cellular response to organonitrogen compound
cellular response to hypoxia
response to camptothecin
regulation of signal transduction by p53 class mediator
regulation of energy homeostasis
negative regulation of glucose import in response to insulin stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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