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Product Details
H00000275-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AMT (AAH07546.1, 1 a.a. approximately 289 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MESLVVGDIA ELRPNQGTLS LFTNEAGGIL DDLIVTNTSE GHLYVVSNAG CWEKDLALMQ DKVRELQNQG RDVGLEVLDN ALLALQGPTA AQVLQAGVAD DLRKLPFMTS AVMEVFGVSG CRVTRCGYTG EDGVEISVPV AGAVHLATAI LKNPEVKLAG LAARDSLRLE AGLCLYGNDI DEHTTPVEGS LSWTLGKRRR AAMDFPGAKV IVPQLKGRVQ RRRVGLMCEG APMRAHSPIL NMEGTKIGTV TSGCPSPSLK KNVAMGYVPC EYSRPGTMLL VELPSGPCF
Target Information
The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE) may be due to a defect in any one of these enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aminomethyltransferase, mitochondrial; GCVT; Glycine cleavage system T protein
Gene Aliases: AMT; GCE; GCST; GCVT; NKH
UniProt ID: (Human) P48728
Entrez Gene ID: (Human) 275
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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