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Product Details
PA5-95123
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human ANGPTL3 (32-48aa EPKSRFAMLDDVKILAN).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806928
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: A549 Cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANG-5; angiopoietin 5; Angiopoietin-5; angiopoietin-like 3; Angiopoietin-like protein 3; Angiopoietin-related protein 3; hypolipidemia
Gene Aliases: ANG-5; ANGPT5; ANGPTL3; ANL3; FHBL2; hypl; UNQ153/PRO179
UniProt ID: (Human) Q9Y5C1, (Mouse) Q9R182
Entrez Gene ID: (Human) 27329, (Mouse) 30924, (Rat) 502970
glycerol metabolic process
fatty acid metabolic process
triglyceride metabolic process
phospholipid metabolic process
cell-matrix adhesion
signal transduction
cholesterol metabolic process
phospholipid catabolic process
negative regulation of phospholipase activity
lipid storage
positive regulation of cell migration
cholesterol homeostasis
negative regulation of catalytic activity
positive regulation of angiogenesis
positive regulation of lipid metabolic process
artery morphogenesis
positive regulation of lipid catabolic process
negative regulation of lipoprotein lipase activity
lipid homeostasis
acylglycerol homeostasis
phospholipid homeostasis
triglyceride homeostasis
angiogenesis
integrin-mediated signaling pathway
response to hormone
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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