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Invitrogen
ANGPTL3 Recombinant Rabbit Monoclonal Antibody (4W9A7)
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ANGPTL3 Antibody (MA5-35681) in IHC (P)
Immunohistochemistry analysis of ANGPTL3 in paraffin-embedded mouse kidney. Samples were incubated with ANGPTL3 Monoclonal antibody (Product # MA5-35681) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
MA5-35681
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
4W9A7
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ANGPTL3 (Q9Y5C1)
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849581
Product Specific Information
Immunogen sequence: MFTIKLLLFI VPLVISSRID QDNSSFDSLS PEPKSRFAML DDVKILANGL LQLGHGLKDF VHKTKGQIND IFQKLNIFDQ SFYDLSLQTS EIKEEEKELR
Target Information
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANG-5; angiopoietin 5; Angiopoietin-5; angiopoietin-like 3; Angiopoietin-like protein 3; Angiopoietin-related protein 3; hypolipidemia
Gene Aliases: ANG-5; ANGPT5; ANGPTL3; ANL3; FHBL2; hypl; UNQ153/PRO179
UniProt ID: (Human) Q9Y5C1, (Mouse) Q9R182
Entrez Gene ID: (Human) 27329, (Mouse) 30924, (Rat) 502970
glycerol metabolic process
fatty acid metabolic process
triglyceride metabolic process
phospholipid metabolic process
cell-matrix adhesion
signal transduction
cholesterol metabolic process
phospholipid catabolic process
negative regulation of phospholipase activity
lipid storage
positive regulation of cell migration
cholesterol homeostasis
negative regulation of catalytic activity
positive regulation of angiogenesis
positive regulation of lipid metabolic process
artery morphogenesis
positive regulation of lipid catabolic process
negative regulation of lipoprotein lipase activity
lipid homeostasis
acylglycerol homeostasis
phospholipid homeostasis
triglyceride homeostasis
angiogenesis
integrin-mediated signaling pathway
response to hormone
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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