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Bioss
ANKLE2 Polyclonal Antibody
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Product Details
BS-9743R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ANKLE2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ankyrin repeat and LEM domain-containing protein 2; LEM domain containing 7; LEM domain-containing protein 4; liver regeneration-related protein LRRG057
Gene Aliases: 1110001J12Rik; Ab2-034; AI661024; ANKLE2; D5Ertd585e; KIAA0692; LEM4; LEMD7; MCPH16; RGD1310191
UniProt ID: (Human) Q86XL3, (Mouse) Q6P1H6
Entrez Gene ID: (Human) 23141, (Mouse) 71782, (Rat) 360829
mitotic nuclear division
mitotic nuclear envelope reassembly
central nervous system development
regulation of protein phosphatase type 2A activity
positive regulation of protein dephosphorylation
negative regulation of phosphorylation
negative regulation of apoptotic process
regulation of catalytic activity
cell division
cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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