Proteintech

ANKRD2 Polyclonal Antibody

ANKRD2 Antibody in Immunocytochemistry (ICC/IF)

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ANKRD2 Antibody (11821-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA) fixed HeLa cells using 11821-1-AP (ANKRD2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

ANKRD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

ANKRD2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11821-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ANKRD2 Fusion Protein Ag2389 (25-327 aa encoded by BC020817)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EAVMDGTME DSEAVQRATA LIEQRLAQEE ENEKLRGDAR QKLPMDLLVL EDEKHHGAQS AALQKVKGQE RVRKTSLDLR REIIDVGGIQ NLIELRKKRK QKKRDALAAS HEPPPEPEEI TGPVDEETFL KAAVEGKMKV IEKFLADGGS ADTCDQFRRT ALHRASLEGH MEILEKLLDN GATVDFQDRL DCTAMHWACR GGHLEVVKLL QSHGADTNVR DKEGDTALHD AVRLNRYKII KLLLLHGADM MTKNLAGKTP TDLVQLWQAD TRHALEHPEP GAEHNGLEGP NDSGRETPQP VPAQ (25-327 aa encoded by BC020817)

Target Information

ANKRD2 may play an important role in skeletal muscle hypertrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Analysis of Masticatory Muscle Tendon-aponeurosis Hyperplasia by Using Next-generation Sequencing.

In vivo (Athens, Greece)

Yumoto M,Mizuno Y,Isozaki Y,Ito KO,Yoda T,Sato T

Mon Mar 07 00:00:00 UTC 2022

Expression of titin-linked putative mechanosensing proteins in skeletal muscle after power resistance exercise in resistance-trained men.

Journal of applied physiology (Bethesda, Md. : 1985)

Wette SG,Birch NP,Soop M,Zügel M,Murphy RM,Lamb GD,Smith HK

Mon Mar 01 00:00:00 UTC 2021

Metronomic 5-Fluorouracil Delivery Primes Skeletal Muscle for Myopathy but Does Not Cause Cachexia.

Pharmaceuticals (Basel, Switzerland)

Campelj DG,Timpani CA,Cree T,Petersen AC,Hayes A,Goodman CA,Rybalka E

Mon May 17 00:00:00 UTC 2021

Ectopic Expression of Ankrd2 Affects Proliferation, Motility and Clonogenic Potential of Human Osteosarcoma Cells.

Cancers

Piazzi M,Kojic S,Capanni C,Stamenkovic N,Bavelloni A,Marin O,Lattanzi G,Blalock W,Cenni V

Wed Jan 06 00:00:00 UTC 2021

Ectopic Expression of Ankrd2 Affects Proliferation, Motility and Clonogenic Potential of Human Osteosarcoma Cells.

Cancers

Piazzi M,Kojic S,Capanni C,Stamenkovic N,Bavelloni A,Marin O,Lattanzi G,Blalock W,Cenni V

Wed Jan 06 00:00:00 UTC 2021

Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts.

PLoS biology

Gao J,Zheng Y,Li L,Lu M,Chen X,Wang Y,Li Y,Liu X,Gao Y,Mao Y,Zhao P,Zhang J,Tang F,Song L,Wen L,Wang J

Sat May 01 00:00:00 UTC 2021

The histone code reader Spin1 controls skeletal muscle development.

Cell death & disease

Greschik H,Duteil D,Messaddeq N,Willmann D,Arrigoni L,Sum M,Jung M,Metzger D,Manke T,Günther T,Schüle R

Thu Nov 23 00:00:00 UTC 2017

The histone code reader Spin1 controls skeletal muscle development.

Cell death & disease

Greschik H,Duteil D,Messaddeq N,Willmann D,Arrigoni L,Sum M,Jung M,Metzger D,Manke T,Günther T,Schüle R

Thu Nov 23 00:00:00 UTC 2017

Characterization of muscle ankyrin repeat proteins in human skeletal muscle.

American journal of physiology. Cell physiology

Wette SG,Smith HK,Lamb GD,Murphy RM

Fri Sep 01 00:00:00 UTC 2017

Emery-Dreifuss Muscular Dystrophy-Associated Mutant Forms of Lamin A Recruit the Stress Responsive Protein Ankrd2 into the Nucleus, Affecting the Cellular Response to Oxidative Stress.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Angori S,Capanni C,Faulkner G,Bean C,Boriani G,Lattanzi G,Cenni V

Tue Jul 11 00:00:00 UTC 2017

Early depression of Ankrd2 and Csrp3 mRNAs in the polyribosomal and whole tissue fractions in skeletal muscle with decreased voluntary running.

Journal of applied physiology (Bethesda, Md. : 1985)

Roberts MD,Childs TE,Brown JD,Davis JW,Booth FW

Sun Apr 01 00:00:00 UTC 2012

Early depression of Ankrd2 and Csrp3 mRNAs in the polyribosomal and whole tissue fractions in skeletal muscle with decreased voluntary running.

Journal of applied physiology (Bethesda, Md. : 1985)

Roberts MD,Childs TE,Brown JD,Davis JW,Booth FW

Sun Apr 01 00:00:00 UTC 2012

Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2).

Molecular biology of the cell

Cenni V,Bavelloni A,Beretti F,Tagliavini F,Manzoli L,Lattanzi G,Maraldi NM,Cocco L,Marmiroli S

Mon Aug 15 00:00:00 UTC 2011

Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2).

Molecular biology of the cell

Cenni V,Bavelloni A,Beretti F,Tagliavini F,Manzoli L,Lattanzi G,Maraldi NM,Cocco L,Marmiroli S

Mon Aug 15 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: ankyrin repeat domain 2 (stretch responsive muscle); Ankyrin repeat domain-containing protein 2; hArpp; mArpp; Skeletal muscle ankyrin repeat protein

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Gene Aliases: ANKRD2; ARPP; mArpp

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UniProt ID: (Human) Q9GZV1, (Mouse) Q9WV06

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Entrez Gene ID: (Human) 26287, (Mouse) 56642, (Rat) 309374

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Function(s)

chromatin binding structural constituent of muscle titin binding protein kinase B binding RNA polymerase II sequence-specific DNA binding transcription factor binding protein binding

Process(es)

negative regulation of transcription from RNA polymerase II promoter regulation of cytokine production negative regulation of myotube differentiation skeletal muscle cell differentiation response to muscle stretch regulation of transcription from RNA polymerase II promoter in response to oxidative stress negative regulation of myoblast differentiation regulation of intrinsic apoptotic signaling pathway by p53 class mediator regulation of myoblast proliferation muscle contraction muscle organ development muscle cell differentiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ANKRD2 Polyclonal Antibody

ANKRD2 Antibody (11821-1-AP) in ICC/IF

Product Details

11821-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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