Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MQELNNEINM QQTVIYQASQ ALNCCVDEEH GKGSLEEAEA ERLLLIATGK RTLLIDELNK LKNEGPQRKN KASPQSEFMP SKGSVTLSEI RLPLKADFVC STVQKPDAAN YYYLIILKAG AENMVATPLA STSNSLNGDA LTFTTTFTLQ DVSNDFEINI EVYSLVQKKD PSGLDKKKKT SKSKAITPKR LLTSITTKSN IHSSVMASPG GLSAVRTSNF ALVGSYTLSL SSVGNTKFVL DKVPFLSSLE GHIYLKIKCQ VNSSVEERGF LTIFEDVSGF GAWHRRWCVL SGNCISYWTY PDDEKRKNPI GRINLANCTS RQIEPANREF CARRNTFELI TVRPQREDDR ETLVSQCRDT LCVTKNWLSA DTKEERDLWM QKLNQVLVDI RLWQPDACYK PIGKP
This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Anillin; DKFZp779A055
Gene Aliases: ANLN; FSGS8; scra; Scraps
UniProt ID: (Human) Q9NQW6
Entrez Gene ID: (Human) 54443
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