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Invitrogen
ANT1/ANT2/ANT3/ANT4 Polyclonal Antibody
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ANT1/ANT2/ANT3/ANT4 Antibody (PA5-109394) in IHC (P)
Immunohistochemistry analysis of ANT1/ANT2/ANT3/ANT4 in paraffin-embedded human colon carcinoma. Samples were incubated with ANT1/ANT2/ANT3/ANT4 Polyclonal antibody (Product # PA5-109394) using a dilution of 1:50 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-109394
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human ANT1 (NP_001142.2).
Conjugate
Form
Liquid
Concentration
1.10 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854805
Product Specific Information
Immunogen sequence: GMLPDPKNVH IFVSWMIAQS VTAVAGLVSY PFDTVRRRMM MQSGRKGADI MYTGTVDCWR KIAKDEGAKA FFKGAWSNVL RGMGGAFVLV LYDEIKKYV
Target Information
ANT1/2/3/4 (SLC25A4, SLC25A5, SLC25A6, SLC25A31) are members of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenine nucleotid translocator 2 fibroblast isoform (ATP-ADP carrier protein); Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocase 4; adenine nucleotide translocase-1; Adenine nucleotide translocator 1; adenine nucleotide translocator 1 (skeletal muscle); adenine nucleotide translocator 1, skeletal muscle; Adenine nucleotide translocator 2; adenine nucleotide translocator 2 (fibroblast); adenine nucleotide translocator 2 fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocator 2, fibroblast isoform (ATP-ADP carrier protein); Adenine nucleotide translocator 4; adenine nucleotide translocator), member 31; adenine nucleotide translocator), member 31-like; ADP,ATP carrier protein 1; ADP,ATP carrier protein 2; ADP,ATP carrier protein 4; ADP,ATP carrier protein, fibroblast isoform; ADP,ATP carrier protein, heart/skeletal muscle; ADP,ATP carrier protein, heart/skeletal muscle isoform T1; ADP/ATP translocase 1; ADP/ATP translocase 2; ADP/ATP translocase 4; ANT 1; ANT 2; ANT 4; heart/skeletal muscle ATP/ADP translocator; mANC1; mitochondrial adenine nucleotide translocator; Mitochondrial S-adenosylmethionine carrier protein; mitochondrial S-adenosylmethionine transporter; S-adenosylmethionine mitochondrial carrier protein; SAM carrier; solute carrier family 25 (mitochondrial adenine nucleotide translocator) member 4; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 31-like; solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 26; solute carrier family 25 (S-adenosylmethionine carrier), member 26; Solute carrier family 25 member 26; Solute carrier family 25 member 31; Solute carrier family 25 member 4; Solute carrier family 25 member 5; solute carrier family 25, member 26; Sperm flagellar energy carrier protein; SZFULLNAME2
Gene Aliases: 1700034J06Rik; 2F1; 4930433D19Rik; 4933433F13Rik; AAC1; AAC2; AAC4; Anc1; ANT; ANT 1; ANT 4; ANT1; ANT2; ANT4; AU019225; AW557176; COXPD28; D6Bwg0781e; MTDPS12; PEO2; PEO3; PEOA2; SAMC; SFEC; SFEC35kDa; SLC25A26; SLC25A31; SLC25A4; SLC25A5; Slc25a6; SZGENESYMBOL2; T1; T2; T3
UniProt ID: (Human) Q70HW3, (Human) Q9H0C2, (Human) P12235, (Human) P05141, (Mouse) Q5U680, (Mouse) Q3V132, (Rat) Q05962, (Mouse) P48962, (Rat) Q09073, (Mouse) P51881
Entrez Gene ID: (Human) 115286, (Human) 83447, (Human) 291, (Human) 292, (Mouse) 67582, (Rat) 362403, (Rat) 689108, (Mouse) 73333, (Rat) 85333, (Mouse) 11739, (Rat) 25176, (Mouse) 11740
transport
S-adenosyl-L-methionine transport
transmembrane transport
S-adenosyl-L-methionine transmembrane transport
translation
liver development
heart development
aging
apoptotic mitochondrial changes
negative regulation of cardiac muscle cell apoptotic process
negative regulation of necroptotic process
positive regulation of cell growth involved in cardiac muscle cell development
response to interleukin-1
negative regulation of mitochondrial membrane permeability involved in apoptotic process
positive regulation of oxidative phosphorylation uncoupler activity
chromosome segregation
positive regulation of cell proliferation
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
mitochondrial genome maintenance
generation of precursor metabolites and energy
adenine transport
viral process
regulation of insulin secretion
ion transport
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