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Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Predicted reactivity: Bovine (80%).
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Amine oxidase [copper-containing] 2; amine oxidase copper containing 2; Amine oxidase copper-containing 2; amine oxidase, copper containing 2 (retina-specific); RAO; Retina-specific copper amine oxidase; Semicarbazide-sensitive amine oxidase; SSAO
Gene Aliases: AOC2; DAO2; RAO
UniProt ID: (Human) O75106
Entrez Gene ID: (Human) 314
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