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Immunogen sequence: GNCCWTQCFG LLRKEAGRLQ RVGGGGGSKY FRTCSRGEHL TIEFENLVES DEGESPGSSH RPLTEEEIVD LRERHYDSIA E
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 94%.
AP1AR is necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. It regulates the membrane association of AP1G1/Gamma1-adaptin, one of the subunits of the AP-1 adapter complex. The direct interaction with AP1G1/Gamma1-adaptin attenuates the release of the AP-1 complex from membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2c18; adapter-related protein complex 1-associated regulatory protein; adaptor-related protein complex 1 associated regulatory protein; Adaptor-related protein complex 1-associated regulatory protein; AP-1 complex-associated regulatory protein; Gadkin; Gamma-1-adaptin brefeldin A resistance protein; Gamma-A1-adaptin and kinesin interactor; gamma1-adaptin brefeldin A resistance protein, gamma-BAR; GBAR
Gene Aliases: 2C18; AP1AR; C4orf16; gamma-BAR; GBAR; PRO0971
UniProt ID: (Human) Q63HQ0
Entrez Gene ID: (Human) 55435
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