Proteintech

AP1M1 Polyclonal Antibody

FIGURE: 1 / 5

AP1M1 Antibody (12112-1-AP) in WB

Human brain tissue were subjected to SDS PAGE followed by western blot with 12112-1-AP (AP1M1 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

AP1M1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

12112-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 7 publications 7 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Dog, Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

AP1M1 Fusion Protein Ag2757 (164-423 aa encoded by BC017469)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: IKYRKNEVF LDVIESVNLL VSANGNVLRS EIVGSIKMRV FLSGMPELRL GLNDKVLFDN TGRGKSKSVE LEDVKFHQCV RLSRFENDRT ISFIPPDGEF ELMSYRLNTH VKPLIWIESV IEKHSHSRIE YMIKAKSQFK RRSTANNVEI HIPVPNDADS PKFKTTVGSV KWVPENSEIV WSIKSFPGGK EYLMRAHFGL PSVEAEDKEG KPPISVKFEI PYFTTSGIQV RYLKIIEKSG YQALPWVRYI TQNGDYQLRT Q (164-423 aa encoded by BC017469)

Target Information

The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Clathrin-associated AP-1 controls termination of STING signalling.

Nature

Liu Y,Xu P,Rivara S,Liu C,Ricci J,Ren X,Hurley JH,Ablasser A

Sat Oct 01 00:00:00 UTC 2022

Dioscin alleviates Alzheimer's disease through regulating RAGE/NOX4 mediated oxidative stress and inflammation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Guan L,Mao Z,Yang S,Wu G,Chen Y,Yin L,Qi Y,Han L,Xu L

Mon Aug 01 00:00:00 UTC 2022

The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4⁺ T cell apoptosis.

Virology

Jacob RA,Johnson AL,Pawlak EN,Dirk BS,Van Nynatten LR,Haeryfar SMM,Dikeakos JD

Fri Sep 01 00:00:00 UTC 2017

The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4⁺ T cell apoptosis.

Virology

Jacob RA,Johnson AL,Pawlak EN,Dirk BS,Van Nynatten LR,Haeryfar SMM,Dikeakos JD

Fri Sep 01 00:00:00 UTC 2017

Adaptor Protein-1 Complex Affects the Endocytic Trafficking and Function of Peptidylglycine α-Amidating Monooxygenase, a Luminal Cuproenzyme.

The Journal of biological chemistry

Bonnemaison ML,Bäck N,Duffy ME,Ralle M,Mains RE,Eipper BA

Fri Aug 28 00:00:00 UTC 2015

AP-1A controls secretory granule biogenesis and trafficking of membrane secretory granule proteins.

Traffic (Copenhagen, Denmark)

Bonnemaison M,Bäck N,Lin Y,Bonifacino JS,Mains R,Eipper B

Wed Oct 01 00:00:00 UTC 2014

AP-1A controls secretory granule biogenesis and trafficking of membrane secretory granule proteins.

Traffic (Copenhagen, Denmark)

Bonnemaison M,Bäck N,Lin Y,Bonifacino JS,Mains R,Eipper B

Wed Oct 01 00:00:00 UTC 2014

AP-1A controls secretory granule biogenesis and trafficking of membrane secretory granule proteins.

Traffic (Copenhagen, Denmark)

Bonnemaison M,Bäck N,Lin Y,Bonifacino JS,Mains R,Eipper B

Wed Oct 01 00:00:00 UTC 2014

AP-1A controls secretory granule biogenesis and trafficking of membrane secretory granule proteins.

Traffic (Copenhagen, Denmark)

Bonnemaison M,Bäck N,Lin Y,Bonifacino JS,Mains R,Eipper B

Wed Oct 01 00:00:00 UTC 2014

Basolateral BMP signaling in polarized epithelial cells.

PloS one

Saitoh M,Shirakihara T,Fukasawa A,Horiguchi K,Sakamoto K,Sugiya H,Beppu H,Fujita Y,Morita I,Miyazono K,Miyazawa K

Mon Dec 09 00:00:00 UTC 2013

Basolateral BMP signaling in polarized epithelial cells.

PloS one

Saitoh M,Shirakihara T,Fukasawa A,Horiguchi K,Sakamoto K,Sugiya H,Beppu H,Fujita Y,Morita I,Miyazono K,Miyazawa K

Mon Dec 09 00:00:00 UTC 2013

Basolateral BMP signaling in polarized epithelial cells.

PloS one

Saitoh M,Shirakihara T,Fukasawa A,Horiguchi K,Sakamoto K,Sugiya H,Beppu H,Fujita Y,Morita I,Miyazono K,Miyazawa K

Mon Dec 09 00:00:00 UTC 2013

Plasma membrane contributes to the formation of pre-autophagosomal structures.

Nature cell biology

Ravikumar B,Moreau K,Jahreiss L,Puri C,Rubinsztein DC

Sun Aug 01 00:00:00 UTC 2010

Plasma membrane contributes to the formation of pre-autophagosomal structures.

Nature cell biology

Ravikumar B,Moreau K,Jahreiss L,Puri C,Rubinsztein DC

Sun Aug 01 00:00:00 UTC 2010

Bioinformatics

Protein Aliases: adapter-related protein complex 1 subunit mu-1; adaptor protein complex AP-1 mu-1 subunit; Adaptor protein complex AP-1 subunit mu-1; adaptor-related protein complex 1 mu 1 subunit; adaptor-related protein complex 1 mu-1 subunit; Adaptor-related protein complex 1 subunit mu-1; adaptor-related protein complex 1, mu 1 subunit; adaptor-related protein complex AP-1, mu subunit 1; AP-1 complex subunit mu-1; AP-mu chain family member mu1A; ap1m1 {ECO:0000312|RGD:1307653}; clathrin adaptor protein AP47; clathrin assembly protein complex 1 medium chain 1; Clathrin assembly protein complex 1 mu-1 medium chain 1; clathrin assembly protein complex 1, medium chain; clathrin assembly protein complex AP1, mu subunit; Clathrin coat assembly protein AP47; Clathrin coat-associated protein AP47; golgi adaptor AP-1 47 kDa protein; Golgi adaptor HA1/AP1 adaptin mu-1 subunit; HA1 47 kDa subunit; Mu-adaptin 1; Mu1A-adaptin

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Gene Aliases: [m]1A; AA408894; Adtm1A; AP1M1; AP47; CLAPM2; CLTNM; MU-1A; mu1A

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UniProt ID: (Human) Q9BXS5, (Rat) Q32Q06, (Mouse) P35585

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Entrez Gene ID: (Human) 8907, (Rat) 306332, (Mouse) 11767

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Function(s)

protein binding

Process(es)

intracellular protein transport vesicle-mediated transport melanosome organization endosome to melanosome transport transport protein transport viral process antigen processing and presentation of exogenous peptide antigen via MHC class II regulation of defense response to virus by virus

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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AP1M1 Polyclonal Antibody

AP1M1 Antibody (12112-1-AP) in WB

Product Details

12112-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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