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Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adaptor. It binds polyphosphoinositides.
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Protein Aliases: 100 kDa coated vesicle protein C; adapter-related protein complex 2 alpha-2 subunit; adapter-related protein complex 2 subunit alpha-2; adaptin alpha A; Adaptin alpha B; adaptin, alpha B; Adaptor protein complex AP-2 subunit alpha-2; adaptor protein complex AP-2, alpha 2 subunit; adaptor related protein complex 2, alpha 2 subunit; Adaptor-related protein complex 2 subunit alpha-2; adaptor-related protein complex 2, alpha 2 subunit; adaptor-related protein complex AP-2, alpha 2 subunit; ADTAA; Alpha adaptin A; Alpha adaptin C; Alpha-adaptin C; alpha-adaptin C; Huntingtin interacting protein J; alpha-C adaptin; Alpha1 adaptin; Alpha2 adaptin; Alpha2-adaptin; AP-2 complex subunit alpha-2; AP2 alpha; AP2A1; CLAPA1; Clathrin assembly; Clathrin assembly protein complex 2 alpha-C large chain; clathrin-associated/assembly/adaptor protein, large, alpha 2; HIP 9; HIP-9; Huntingtin yeast partner J; Huntingtin-interacting protein 9; Huntingtin-interacting protein J; Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit
Gene Aliases: 2410074K14Rik; ADTAB; AF006990; AP2A2; AW146353; C78001; CLAPA2; HIP-9; HIP9; HYPJ; KIAA0899; L25
UniProt ID: (Human) O94973, (Mouse) P17427
Entrez Gene ID: (Human) 161, (Mouse) 11772
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