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AP3B1 Antibody (PA5-106298) in IHC (P)
Immunohistochemistry analysis of AP3B1 in rat stomach tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with AP3B1 polyclonal antibody (Product # PA5-106298) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106298
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human AP3B1(Accession O00203), corresponding to amino acid residues I936-V986.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853975
Product Specific Information
Antibody detects endogenous levels of total AP3B1.
Target Information
AP3B1 is a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Structurally, AP3B1 is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in AP3B1 are associated with Hermansky-Pudlak syndrome type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adapter-related protein complex 3 subunit beta-1; adaptor protein complex AP-3 beta-1 subunit; Adaptor protein complex AP-3 subunit beta-1; adaptor related protein complex 3, beta 1 subunit; Adaptor-related protein complex 3 subunit beta-1; adaptor-related protein complex 3, beta 1 subunit; adaptor-related protein complex AP-3, beta 1 subunit; AP-3 complex beta-3A subunit; AP-3 complex subunit beta-1; ap3; Beta-3A-adaptin; beta3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chain; recombination induced mutation 2
Gene Aliases: ADTB3; ADTB3A; AP-3; AP3B1; AU015684; beta3A; C78395; HPS; HPS2; PE; pearl; rim2
UniProt ID: (Human) O00203, (Mouse) Q9Z1T1
Entrez Gene ID: (Human) 8546, (Mouse) 11774, (Rat) 309969
protein targeting to lysosome
transport
zinc II ion transport
intracellular protein transport
blood coagulation
anterograde axonal transport
protein transport
vesicle-mediated transport
antigen processing and presentation
melanosome organization
antigen processing and presentation, exogenous lipid antigen via MHC class Ib
anterograde synaptic vesicle transport
positive regulation of NK T cell differentiation
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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