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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • APC6 Antibodies

          Invitrogen

          APC6 Recombinant Rabbit Monoclonal Antibody (SD085-8)

          1 Published Figure
          2 References
          View all (17) APC6 antibodies

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          Datasheet
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          Datasheet
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          Cite APC6 Recombinant Rabbit Monoclonal Antibody (SD085-8)

          • Antibody Testing Data (4)
          • Published Figures (1)
          APC6 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          APC6 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          APC6 Antibody (MA5-32406) in ICC/IF

          Immunocytochemical analysis of APC6 in RH-35 cells using a APC6 Monoclonal antibody (Product # MA5-32406) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          APC6 Antibody in Immunocytochemistry (ICC/IF)
          APC6 Antibody in Immunocytochemistry (ICC/IF)
          APC6 Antibody in Immunocytochemistry (ICC/IF)
          APC6 Antibody in Western Blot (WB)
          APC6 Antibody in Western Blot (WB)

          Product Details

          MA5-32406

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:2,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          -
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          SD085-8

          Immunogen

          Recombinant protein within Human APC6 aa 181-247
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

          Contains

          0.05% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2809684

          Product Specific Information

          Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

          Target Information

          The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Anaphase-promoting complex subunit 6; anaphase-promoting complex, subunit 6; APC6; CDC16 cell division cycle 16 homolog; CDC16 homolog; CDC16Hs; cell division cycle 16 homolog; Cell division cycle protein 16 homolog; Cyclosome subunit 6; RP11-569D9.4

          View more View less

          Gene Aliases: 2700071J12Rik; 2810431D22Rik; ANAPC6; APC6; CDC16; CDC16Hs; CUT9

          View more View less

          UniProt ID: (Human) Q13042, (Mouse) Q8R349

          View more View less

          Entrez Gene ID: (Human) 8881, (Rat) 290875, (Mouse) 69957

          View more View less

          Function(s)
          protein binding
          Process(es)
          mitotic nuclear division regulation of mitotic nuclear division cell proliferation anaphase-promoting complex-dependent catabolic process protein ubiquitination involved in ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle protein K11-linked ubiquitination cell cycle
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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