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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • APLF Antibodies

          Invitrogen

          APLF Polyclonal Antibody

          View all (8) APLF antibodies
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          Datasheet
          Protocols
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          Cite APLF Polyclonal Antibody

          • Antibody Testing Data (2)
          APLF Antibody in Immunocytochemistry (ICC/IF)
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          APLF Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          APLF Antibody (PA5-57001) in ICC/IF

          Immunofluorecent analysis of APLF in human cell line A-431 using APLF Polyclonal Antibody (Product # PA5-57001). Staining shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          APLF Antibody in Immunocytochemistry (ICC/IF)
          APLF Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          PA5-57001

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human APLF. Recombinant protein control fragment (Product #RP-102626).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2638072

          Product Specific Information

          Immunogen sequence: SQLEGSTEIA KTQMTPTNSV SFLGENRDCN KQQPILAERK RILPTWMLAE HLSDQNLSVP AISGGNVIQG SGKEEICKDK SQLN

          Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 48%.

          Target Information

          C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks.[supplied by OMIM, Mar 2008].

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Aprataxin and PNK-like factor; aprataxin- and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; XRCC1-interacting protein 1; zinc finger, CX5CX6HX5H motif containing 1

          View more View less

          Gene Aliases: APFL; APLF; C2orf13; PALF; XIP1; ZCCHH1

          View more View less

          UniProt ID: (Human) Q8IW19

          View more View less

          Entrez Gene ID: (Human) 200558

          View more View less

          Function(s)
          nucleotide binding DNA-(apurinic or apyrimidinic site) lyase activity endodeoxyribonuclease activity protein binding 3'-5' exonuclease activity metal ion binding
          Process(es)
          single strand break repair double-strand break repair cellular response to DNA damage stimulus regulation of isotype switching positive regulation of DNA ligation nucleic acid phosphodiester bond hydrolysis
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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