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Proteintech
APOA4 Monoclonal Antibody (3A9A8)
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Product Details
66252-1-IG
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3A9A8
Immunogen
APOA4 Fusion Protein Ag12454 (23-396 aa encoded by BC074764)
Conjugate
Form
Liquid
Concentration
0.79 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SADQVATVM WDYFSQLSNN AKEAVEHLQK SELTQQLNAL FQDKLGEVNT YAGDLQKKLV PFATELHERL AKDSEKLKEE IGKELEELRA RLLPHANEVS QKIGDNLREL QQRLEPYADQ LRTQVNTQAE QLRRQLTPYA QRMERVLREN ADSLQASLRP HADELKAKID QNVEELKGRL TPYADEFKVK IDQTVEELRR SLAPYAQDTQ EKLNHQLEGL TFQMKKNAEE LKARISASAE ELRQRLAPLA EDVRGNLRGN TEGLQKSLAE LGGHLDQQVE EFRRRVEPYG ENFNKALVQQ MEQLRQKLGP HAGDVEGHLS FLEKDLRDKV NSFFSTFKEK ESQDKTLSLP ELEQQQEQQQ EQQQEQVQML APLES (23-396 aa encoded by B C074764)
Target Information
Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is an O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but evidence from several in vitro studies indicate that this apolipoprotein is involved in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apo-AIV; apoA-IV; Apolipoprotein A-IV; Apolipoprotein A4; MGC142154; MGC142156
Gene Aliases: APOA4
UniProt ID: (Human) P06727
Entrez Gene ID: (Human) 337
retinoid metabolic process
innate immune response in mucosa
cholesterol biosynthetic process
lipid transport
response to lipid hydroperoxide
leukocyte cell-cell adhesion
cholesterol metabolic process
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
removal of superoxide radicals
regulation of intestinal cholesterol absorption
neuron projection regeneration
regulation of cholesterol transport
cholesterol efflux
phospholipid efflux
chylomicron remodeling
very-low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
chylomicron assembly
high-density lipoprotein particle assembly
negative regulation of plasma lipoprotein particle oxidation
response to stilbenoid
lipoprotein metabolic process
lipoprotein biosynthetic process
cholesterol homeostasis
hydrogen peroxide catabolic process
reverse cholesterol transport
multicellular organism lipid catabolic process
cellular protein metabolic process
positive regulation of fatty acid biosynthetic process
phosphatidylcholine metabolic process
positive regulation of lipoprotein lipase activity
lipid homeostasis
protein-lipid complex assembly
triglyceride homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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