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Product Details
PA5-75483
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 67-112 of Human APOBEC3A.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719211
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
PHO1 a member of the cytidine deaminase gene family. The PHO1 gene is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. This gene encodes a protein that lacks the zinc binding activity and may be an expressed pseudogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A3A; apolipoprotein B editing complex 3; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3A; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A; Apolipoprotein B mRNA-editing complex 3; Arp3; CEM-15; CEM15; DNA dC->dU-editing enzyme APOBEC-3; DNA dC->dU-editing enzyme APOBEC-3A; PHO-1; pho1; phorbolin 1; Phorbolin-1; Phorbolin1; probable DNA dC->dU-editing enzyme APOBEC-3A; recovery from Friend virus 3
Gene Aliases: A3A; Apobec3; APOBEC3A; ARP3; BC003314; bK150C2.1; Cem15; PHRBN; Rfv3
UniProt ID: (Human) P31941, (Mouse) Q99J72
Entrez Gene ID: (Human) 200315, (Mouse) 80287
cytidine deaminase activity
protein binding
zinc ion binding
deoxycytidine deaminase activity
catalytic activity
GTP cyclohydrolase activity
tRNA-specific adenosine deaminase activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
N-cyclopropylmelamine deaminase activity
N-cyclopropylammeline deaminase activity
N-cyclopropylammelide alkylamino hydrolase activity
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity
tRNA-specific adenosine-37 deaminase activity
archaeal-specific GTP cyclohydrolase activity
poly(A) RNA binding
metal ion binding
tRNA-specific adenosine-34 deaminase activity
hematopoietic progenitor cell differentiation
immune system process
metabolic process
negative regulation of transposition
negative regulation of viral genome replication
innate immune response
defense response to virus
cytidine deamination
clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine
DNA cytosine deamination
cellular response to xenobiotic stimulus
DNA demethylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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