Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
APOBEC3A Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 6
APOBEC3A Antibody (PA5-99584) in IHC (P)
Immunohistochemistry analysis of APOBEC3A in human pancreatic cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with APOBEC3A polyclonal antibody (Product # PA5-99584) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-99584
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human APOBEC3A(Accession P31941), corresponding to amino acid residues I26-L76.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2818517
Product Specific Information
The immunogen sequence for PA5-99584 is VKMDQHRGFLHN.
Antibody detects endogenous levels of total APOBEC3A.
Target Information
PHO1 a member of the cytidine deaminase gene family. The PHO1 gene is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. This gene encodes a protein that lacks the zinc binding activity and may be an expressed pseudogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A3A; apolipoprotein B editing complex 3; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3A; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A; Apolipoprotein B mRNA-editing complex 3; Arp3; CEM-15; CEM15; DNA dC->dU-editing enzyme APOBEC-3; DNA dC->dU-editing enzyme APOBEC-3A; PHO-1; pho1; phorbolin 1; Phorbolin-1; Phorbolin1; probable DNA dC->dU-editing enzyme APOBEC-3A; recovery from Friend virus 3
Gene Aliases: A3A; Apobec3; APOBEC3A; ARP3; BC003314; bK150C2.1; Cem15; PHRBN; Rfv3
UniProt ID: (Human) P31941, (Mouse) Q99J72
Entrez Gene ID: (Human) 200315, (Mouse) 80287
cytidine deaminase activity
protein binding
zinc ion binding
deoxycytidine deaminase activity
catalytic activity
GTP cyclohydrolase activity
tRNA-specific adenosine deaminase activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
N-cyclopropylmelamine deaminase activity
N-cyclopropylammeline deaminase activity
N-cyclopropylammelide alkylamino hydrolase activity
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity
tRNA-specific adenosine-37 deaminase activity
archaeal-specific GTP cyclohydrolase activity
poly(A) RNA binding
metal ion binding
tRNA-specific adenosine-34 deaminase activity
hematopoietic progenitor cell differentiation
immune system process
metabolic process
negative regulation of transposition
negative regulation of viral genome replication
innate immune response
defense response to virus
cytidine deamination
clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine
DNA cytosine deamination
cellular response to xenobiotic stimulus
DNA demethylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support