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Immunogen sequence: AMYPHIFYFH FKNLLKACGR NESWLCFTME VTKHHSAVFR KRGVFRNQVD PETHCHAERC FLSWFCDDIL SPNTNYEVTW YTSWSPCPEC AGEVAEFLAR HSNVNLTIFT ARLCYFWDTD YQEGLCSLSQ EGASVKIMGY KDFVSCWKNF VYSDDEPFKP WKGLQTNFRL LKRRLREILQ; Positive Samples: Raji, HepG2, 293T, Mouse Spleen, Mouse liver, Mouse kidney, Rat liver, Rat kidney; Cellular Location: Cytoplasm, P-body
This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3E pseudogene; probable DNA dC->dU-editing enzyme APOBEC-3D
Gene Aliases: A3D; APOBEC3DE; APOBEC3E; ARP6
Entrez Gene ID: (Human) 140564
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