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Proteintech
ARFGAP1 Polyclonal Antibody
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Product Details
13571-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARFGAP1 Fusion Protein Ag4468 (1-414 aa encoded by BC028233)
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASPRTRKV LKEVRVQDEN NVCFECGAFN PQWVSVTYGI WICLECSGRH RGLGVHLSFV RSVTMDKWKD IELEKMKAGG NAKFREFLES QEDYDPCWSL QEKYNSRAAA LFRDKVVALA EGREWSLESS PAQNWTPPQP RTLPSMVHRV SGQPQSVTAS SDKAFEDWLN DDLGSYQGAQ GNRYVGFGNT PPPQKKEDDF LNNAMSSLYS GWSSFTTGAS RFASAAKEGA TKFGSQASQK FWGHKQQPEP ASELGHSLNE NVLKPAQEKV KEGKIFDDVS SGVSQLASKG VGSKGWRDVT TFFSGKAEGP LDSPSEGHSY QNSGLDHFQN SNIDQSFWET FGSAEPTKTR KSPSSDSWTC ADTSTERRSS DSWEVWGSAS TNRNSNSDGG EGGEGTKKAV PPAVPTDDGW DNQNW (1-414 aa encoded by BC028233)
Target Information
ArfGAP1 is a 406 amino acid containing regulatory protein with an Arf-GAP domain known to be involved in the activation of the GTPase activity of ADP ribosylation factor (ARF). ArfGAP1, a GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1), promotes the hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles thus playing an important role in membrane trafficking and/or vesicle transport. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been reported. Ubiquitous expression of ArfGAP1 is seen in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADP-ribosylation factor 1 GTPase activating protein; ADP-ribosylation factor 1 GTPase-activating protein; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase-activating protein 1; ARF GAP 1; ARF1 GAP; ARF1-directed GTPase-activating protein; GAP protein; RP11-261N11.1
Gene Aliases: AI115377; Arf GAP1; ARF1GAP; ARFGAP1; HRIHFB2281
UniProt ID: (Human) Q8N6T3, (Rat) Q62848, (Mouse) Q9EPJ9
Entrez Gene ID: (Human) 55738, (Rat) 246310, (Mouse) 228998
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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