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Product Details
PA5-57800
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ARGBP2. Recombinant protein control fragment (Product #RP-95659).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2638124
Product Specific Information
Immunogen sequence: PRDSPRAISF KNGWQMARQN AEIWSSTEET VSPKIKSRSC DDLLNDDCDS FPDPKVKSES MGSLLCEEDS KESCPMAWGS PYVPEVRSNG RSR
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 84%.
Target Information
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Arg binding protein 2; Arg-binding protein 2; Arg/Abl-interacting protein 2; ArgBP2; Sorbin; Sorbin and SH3 domain-containing protein 2
Gene Aliases: ARGBP2; KIAA0777; PRO0618; SORBS2
UniProt ID: (Human) O94875
Entrez Gene ID: (Human) 8470
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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