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ARHGAP10 Antibody (PA5-24188) in IHC (P)
Immunohistochemistry analysis of ARHGAP10 in formalin fixed and paraffin embedded human skeletal muscle. Samples were incubated with ARHGAP10 polyclonal antibody (Product # PA5-24188) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-24188
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 237-263 amino acids from the central region of human ARHGAP10
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2541688
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Graf-related protein 2; GRAF2; GTPase regulator associated with focal adhesion kinase 2; Rho GTPase-activating protein 10; Rho-type GTPase-activating protein 10
Gene Aliases: ARHGAP10; GRAF2; PS-GAP; PSGAP
UniProt ID: (Human) A1A4S6
Entrez Gene ID: (Human) 79658
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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