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Immunogen sequence: VPPCLTTSAP LIRRQLSHDH ESVGPPSLDA QPNSKTERSK SYDEGLDDYR EDAKLSFKHV SSLKGIKIAD SQKSSEDSGS RKDSSSEVFS DAAKEG
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.
Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Rho GTPase-activating protein 10; Rho GTPase-activating protein 21; Rho-GTPase activating protein 10; Rho-type GTPase-activating protein 21
Gene Aliases: ARHGAP10; ARHGAP21; KIAA1424
UniProt ID: (Human) Q5T5U3
Entrez Gene ID: (Human) 57584
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