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Product Details
BS-9296R
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ARHGAP32, amino acids 860-896.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain-specific Rho GTP-ase-activating protein; Brain-specific Rho GTPase-activating protein; GAB-associated CDC42; GAB-associated Cdc42/Rac GTPase-activating protein; GC-GAP; GTPase regulator interacting with TrkA; GTPase-activating protein for Cdc42 and Rac1; p200RhoGAP; p250GAP; rac GTPase activating protein; Rho GTPase activating protein 32; Rho GTPase activating protein 33 pseudogene; Rho GTPase-activating protein 32; Rho-type GTPase-activating protein 32; Rho/Cdc42/Rac GTPase-activating protein RICS; RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling; RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling
Gene Aliases: 3426406O18Rik; ARHGAP32; GC-GAP; GRIT; KIAA0712; mKIAA0712; p200RhoGAP; p250GAP; PX-RICS; RICS
UniProt ID: (Human) A7KAX9, (Mouse) Q811P8
Entrez Gene ID: (Human) 9743, (Rat) 315530, (Mouse) 330914
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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