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Proteintech
ARHGAP4 Polyclonal Antibody
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Product Details
16697-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARHGAP4 Fusion Protein Ag10091 (714-986 aa encoded by BC052303)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VALQGRVNQ LVQTLIVQPD RVFPPLTSLP GPVYEKCMAP PSASCLGDAQ LESLGADNEP ELEAEMPAQE DDLEGVVEAV ACFAYTGRTA QELSFRRGDV LRLHERASSD WWRGEHNGMR GLIPHKYITL PAGTEKQVVG AGLQTAGESG SSPEGLLASE LVHRPEPCTS PEAMGPSGHR RRCLVPASPE QHVEVDKAVA QNMDSVFKEL LGKTSVRQGL GPASTTSPSP GPRSPKAPPS SRLGRNKGFS RGPGAPASPS ASHPQGLDTT PKPH (714-986 aa encoded by B C052303)
Target Information
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: p115; RG RhoGAP4; Rho GTPase-activating protein 4; Rho-GAP hematopoietic protein C1; Rho-type GTPase-activating protein 4
Gene Aliases: ARHGAP4; C1; KIAA0131; p115; RGC1; RHOGAP4; SrGAP4
UniProt ID: (Human) P98171
Entrez Gene ID: (Human) 393
cytoskeleton organization
Rho protein signal transduction
positive regulation of signal transduction
negative regulation of fibroblast migration
negative regulation of cell migration
negative regulation of axon extension
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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