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Proteintech
ARHGDIB Monoclonal Antibody (3E7B7)
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Product Details
66054-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat,
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
3E7B7
Immunogen
ARHGDIB Fusion Protein Ag9091 (1-201 aa encoded by BC009200)
Conjugate
Form
Liquid
Concentration
1.01 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTEKAPEPH VEEDDDDELD SKLNYKPPPQ KSLKELQEMD KDDESLIKYK KTLLGDGPVV TDPKAPNVVV TRLTLVCESA PGPITMDLTG DLEALKKETI VLKEGSEYRV KIHFKVNRDI VSGLKYVQHT YRTGVKVDKA TFMVGSYGPR PEEYEFLTPV EEAPKGMLAR GTYHNKSFFT DDDKQDHLSW EWNLSIKKEW TE (1-201 aa encoded by BC009200)
Target Information
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: D4; d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta
Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2
UniProt ID: (Human) P52566, (Mouse) Q61599
Entrez Gene ID: (Human) 397, (Rat) 362456, (Mouse) 11857
regulation of catalytic activity
cellular response to redox state
metabolic process
negative regulation of trophoblast cell migration
movement of cell or subcellular component
negative regulation of cell adhesion
multicellular organism development
regulation of Rho protein signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
regulation of actin cytoskeleton reorganization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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